Help with writing 2 pages about treatment for sickle cell disease

write 2 pages 12-time new roman double space about: 

Long-term nitrite treatment for sickle cell disease.What is the tolerance?

What are the levels in blood and tissue? does these level decreases over time 

don’t include a definition of sickle cell disease or about nitric oxide generatione from nitrite in the body, I allready wrote about it.

 
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